有高线粒体RNA含量的纤维细胞和髓状细胞代表了OA同胞体内的生物学意义上的种群

Wesley Tran1, Garth Blackler1, Rebecca Luo1

  • 1Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada; Bone and Joint Institute, University of Western Ontario, London, ON, Canada.

PubMed
概括

骨关节炎 (OA) 中高线粒体RNA含量 (pMT) 细胞是可活的和与疾病相关的,不会受到压力或死亡. 排除这些细胞可能会掩盖关键的骨关节炎病理生物学,需要特定于环境的质量控制策略.

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