中国和美国心脏代谢多病症预测因子的比较分析:一种机器学习方法
Jingjing Zhu1, Zumin Shi2, Zongyuan Ge3
1School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Diabetes research and clinical practice
|October 14, 2025
概括
开发一种双向机器学习模型用于心脏代谢多病症 (CMM) 查,确定了关键的风险因素. 针对中国和美国的量身定制的查策略改善了对心血管疾病 (CVD) 和代谢疾病 (MD) 的早期检测.
科学领域:
- 公共卫生 公共卫生
- 计算生物学 计算生物学
- 流行病学 流行病学
背景情况:
- 心脏代谢多病症 (CMM),心血管疾病 (CVD) 和代谢疾病 (MD) 的同时发生,构成了全球重大健康挑战.
- 目前对CMM的查工具不足,在不同国家之间缺乏适用性,特别是在美国和中国之间.
- 需要先进的,跨国适用的查方法来识别有CMM风险的个体.
研究的目的:
- 开发和验证一种双向机器学习 (ML) 模型,用于预测心脏代谢多病症 (CMM) 风险.
- 确定中国和美国的CMM的独特和共同的风险因素.
- 为了实现精确的查,并为CMM提供特定区域的公共卫生干预信息.
主要方法:
- 利用了来自中国健康与退休长度调查 (CHARLS) 和美国健康与退休研究 (HRS) 的数据.
- 开发和比较双向ML模型,包括后勤回归 (LR),高斯天真贝叶斯 (GNB) 和极端梯度增强 (XGBoost).
- 使用曲线下的面积 (AUC) 评估模型性能,并通过SHAP分析进行跨国验证以确定预测因素.
主要成果:
- 后勤回归模型在预测心血管疾病 (CVD) 方面表现强 (AUC = 0.70在两个国家).
- 对代谢性疾病 (MD) 的预测准确性各不相同,LR (AUC = 0.71) 在中国和GNB (AUC = 0.65) 在美国的优势.
- 核心预测因素包括疾病数量和适度的体力活动,并确定了独特的区域预测因素,如中国的握力和美国的脉/情绪问题.
结论:
- 一个经过验证的,双向的ML模型为在不同国家进行精确的CMM查提供了一个有前途的工具.
- 建议采用特定区域的查策略,强调中国的握力和平衡,美国的脉冲监测和心理干预.
- 这种方法促进了有针对性的公共卫生干预措施,以减轻心脏代谢多病症的负担.
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