当与超声波风险相结合时,甲状腺结节的诊断准确性具有不确定的细胞学
Shaza A Samargandy1, Yousef Z Khedher1, Ghaida A Alzahrani1
1From the Endocrine Unit, Department of Medicine (Samargandy); Department of Medicine (Khedher, Alzahrani, Nahhas, Alshaikh, Alzahrani); Department of Community (Samargandy); and Department of Radiology (Ghoneim), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Saudi medical journal
|October 14, 2025
概括
超声波风险水平提高甲状腺结节的诊断不确定的细胞学 (贝塞斯达III/IV). 高风险的超声波发现支持手术,提高了诊断准确度,而不是重复细针吸收细胞学.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 甲状腺结节很常见,不确定的细胞学 (贝塞斯达III/IV) 构成诊断挑战.
- 准确的风险分层对于适当的管理至关重要,平衡了对手术的需要和不必要的程序.
研究的目的:
- 评估超声波 (US) 在甲状腺结核中的风险分层的额外诊断价值,使用贝塞斯达III (意义不明的卵泡病变 - FLUS) 和IV (卵泡瘤 - FN) 细胞学.
- 为了确定美国特征是否可以改善未确定甲状腺结节的决策.
主要方法:
- 对接受甲状腺切除术 (2016-2023) 的患者的290个甲状腺结节进行了回顾性分析.
- 使用贝塞斯达系统和基于2015年美国甲状腺协会 (ATA) 准则的美国风险分层评估细针吸收细胞学 (FNAC).
- 计算每个美国和FNAC类别的恶性瘤率.
主要成果:
- 恶性瘤的发病率为FLUS的36.9%,FN的50%.
- 在不确定的细胞学中,高风险的美国特征显示了47%的敏感性和81%的特异性.
- 将FLUS/FN与高风险的美国特征结合起来,提高了对50%的敏感性和80%的特异性.
结论:
- 超声波风险分层为不确定的甲状腺细胞学提供了有价值的诊断信息.
- 贝塞斯达III/IV结节中的高风险美国发现可以指导手术决策,可能避免重复FNAC或观察.
- 美国的特点是帮助管理具有不确定的细胞学的甲状腺结节,优化患者护理途径.
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