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在高血压人口中,围脂肪厚度与患高血压的风险之间的关联是正常的高血压
Suining Xu1, Tingting Zheng1, Xiyang Li1
1Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
增加周周脂肪厚 (PRFT) 与高血压患者患高血压的风险较高有关. 尿中的白蛋白与肌素比率 (ACR) 部分解释了这种关联.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心脏病学 心脏病学
- 医疗成像医学成像
背景情况:
- 周周脂肪组织在高血压进展中的作用尚未完全理解.
- 研究围脂肪厚度 (PRFT) 提供了对高血压发展的见解.
研究的目的:
- 为了检查围脂肪厚度 (PRFT) 和高血压发展之间的关联.
- 评估PRFT在高血压正常人群中的预测价值.
主要方法:
- 166名高血压正常的受试者接受了围膜超声波脂肪厚度测量.
- 一年后的随访评估高血压发生率.
- 使用多变量逻辑回归和调解分析.
主要成果:
- 较高的PRFT与高血压发病率增加相关 (27.6%对比7.8%).
- 在调整为混因子 (OR=1.085) 后,PRFT仍然与高血压有显著的关联.
- 尿中的白蛋白与肌素比率 (ACR) 介导了PRFT与高血压的联系的25.59%.
结论:
- 增加周围脂肪厚度是高血压患者高血压正常的高血压的风险因素.
- 尿路ACR部分调解了PRFT和高血压进展之间的关系.
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