R-P 时间比:下肢动脉血动力学评估的新型指数
Jun Fujisaki1, Makoto Utsunomiya2, Makiko Kaneko1
1Department of Clinical Functional Physiology, Toho University Ohashi Medical Center, Meguro-Ku, Tokyo, Japan.
Ultrasound in medicine & biology
|October 14, 2025
概括
R-P时间比率 (RPR) 可能比脚-手臂指数 (ABI) 提供更准确的下肢动力学评估,特别是在膝盖以下的病变. 这一新指数显示,在内血管治疗 (EVT) 后的显著改善.
科学领域:
- 血管医学 血管医学
- 诊断性超声波 超声波 超声波 超声波
- 血液动力学 血液动力学
背景情况:
- 脚-手臂指数 (ABI) 是下肢动脉评估的标准,但对于患有静脉硬化 obliterans 的患者来说是不够的,特别是膝盖以下的病变.
- 糖尿病和透析患者的患病率越来越高,导致动脉样硬化症的增加,需要改进诊断方法.
- 建议R-P时间比 (RPR) 作为这些具有挑战性的病例的潜在更有效的血液动力学评估工具.
研究的目的:
- 为了比较ABI和RPR在评估下肢动脉血动力学方面的有效性.
- 评估ABI和RPR在评估内血管治疗 (EVT) 后血流改善方面的实用性.
- 调查RPR作为血液动力学评估的新型指数,特别是在膝盖以下病变的情况下.
主要方法:
- 一项涉及对照组 (107名患者) 和病变组 (102名患者) 进行EVT的比较研究.
- 在EVT前后进行双重超声波和ABI测量.
- 使用脉冲多普勒测量共动脉 (CFA),前动脉 (ATA) 和后动脉 (PTA) 的R-P时间;计算RPR (ATA/CFA和PTA/CFA).
主要成果:
- 与对照组相比,损伤组表现出明显较低的ABI和较高的RPR.
- RPR与ABI显示出明显的负相关性 (r = -0.677).
- 无论是ABI还是RPR,在EVT后,膝盖上部病变均显著改善,而RPR在膝盖下部病变方面显著改善.
结论:
- 与ABI相比,RPR显示为一个新的指标,用于更准确地对下肢动脉进行血液动力学评估.
- 在评估膝下动脉病变时,RPR可能特别有价值.
- 这项研究表明,RPR在评估EVT后治疗有效性的有用性.
相关概念视频
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
358
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
358
01:11Pulse Assessment Sites
2.5K
Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
2.5K
01:16Pulse
2.0K
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
2.0K
01:11Assessment of radial pulse
1.4K
Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
1.4K
01:27Assessment of the Cardiovascular System III: Palpation
1.0K
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
1.0K
01:25Assessment of apical radial pulse
1.2K
Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
1.2K