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海洋黄瓜的染色体级基因组组合,Colochirus anceps

Chunxi Jiang^1,2,3, Qianwen Wu^1,2,3, Fang Su^1,2,3

¹Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China.

Scientific data

|October 14, 2025

概括

产生了第一个染色体水平的基因组组合,用于海黄瓜Colochirus anceps (Dendrochirotida序列). 这种高质量的基因组提供了关于海基因组学,适应性和多样性的见解.

科学领域:

海洋生物学海洋生物学
基因组学就是基因组学.
动物学动物学

背景情况:

科洛希鲁斯 (Colochirus anceps) 是一种盆地海黄瓜,表现出异血色彩,并在营养物质回收过程中发挥作用.
海黄瓜 (Holothuroidea) 是具有生态意义的海洋无脊椎动物,具有潜在的生物医学应用.
目前缺乏Dendrochirotida序列的基因组资源.

研究的目的:

为了产生第一个染色体水平的基因组组合的Colochirus anceps.
为Dendrochirotida序列提供一个基础的基因组资源.
为了使未来的研究能够研究海黄瓜的生物学,进化和适应.

主要方法:

使用了Illumina短读,PacBio HiFi长读和Hi-C测序技术的组合.
组装了C. anceps. 的染色体级基因组.
标注的蛋白质编码基因和通过BUSCO分析评估基因组的完整性.

主要成果:

产生了2,238.33 Mb的染色体级基因组组合,定在23个染色体上,结合N50为15.09 Mb.
鉴定了24,102个编码蛋白质的基因,并观察到高重复含量为70.95%.
通过BUSCO分析获得了94.3%的基因组完整度得分.

结论:

这项研究提出了第一个高质量的基因组组合,为订单Dendrochirotida.
C. anceps 基因组为海黄的基因组架构和进化历史提供了宝贵的见解.
这种资源将有助于进一步探索海黄瓜的独特特征,适应能力和多样性.

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