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Updated: Jan 15, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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GRIN2A无变体具有早期精神分裂症和其他精神障碍的高风险,并可能使精确治疗成为可能

Johannes R Lemke1,2, Andrea Eoli3,4, Ilona Krey5,6

  • 1Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany. johannes.lemke@medizin.uni-leipzig.de.

Molecular psychiatry
|October 14, 2025
PubMed
概括

罕见的GRIN2A基因变异与精神分裂症等早期发病的精神障碍有关. 在受影响个体中,L-氨酸治疗有望改善神经精神病症状.

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