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Updated: Jan 15, 2026

Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo
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Published on: June 2, 2019

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乌比基林-2液滴催化α-synuclein纤维的形成

Tomoki Takei1,2, Yukiko Sasazawa1,2,3,4, Daisuke Noshiro5

  • 1Department of Neurology, Juntendo University Faculty of Medicine, Tokyo, Japan.

The EMBO journal
|October 14, 2025
PubMed
概括

乌比基林-2 (UBQLN2) 滴,而不是α-synuclein (α-syn) LLPS,促进了帕金森病的病理学. UBQLN2滴滴催化α-syn纤维的形成,为神经退行性疾病提供治疗点.

关键词:
液体液相分离器 液相分离器帕金森氏症 帕金森氏症乌比奎林-2是一种α-synuclein 是一种同核蛋白.

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