脑部与年龄相关的变化之间的关系通过普通头部计算机断层扫描检测和咳测试结果结果
Rena Murase1,2, Ayako Nakane3,4, Yumiko Omosu5
1Department of Dysphagia Rehabilitation, Division of Gerontology and Gerodontology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549, Japan.
咳反射可能随着年龄的增长而减弱,可能与大脑变化有关. 这项研究在老年人中发现头部CT扫描与咳测试结果相关的脑白质病变.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 肺部病理学 肺部病理学
背景情况:
- 咳反射被认为在健康的老年人中保持不变,但临床观察表明潜在的下降.
- 大脑与年龄相关的变化通常通过成像检测到,但更简单的查方法是可取的.
研究的目的:
- 为了研究与年龄相关的大脑变化和老年人的咳反射功能之间的关系.
- 为了确定咳测试结果是否与简单的头部计算机断层扫描 (CT) 结果相关.
主要方法:
- 一项追溯观察性研究,涉及169名65岁及以上的患者.
- 简单的头部CT检测结果和咳检测结果的统计分析,使用千平方测试和逻辑回归.
主要成果:
- 在169名参与者中,有160人 (94.6%) 在CT上显示了与年龄相关的大脑变化.
- 咳测试结果与性别,大脑白质变化和肺炎有显著的关联.
- 后勤回归确定脑白质病变和肺炎是影响咳测试结果的重要因素.
结论:
- 在简单的头部CT上出现大脑白质病变与咳测试结果有关.
- 这项研究表明,与年龄相关的大脑变化和咳反射之间存在潜在的关联.
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