散布的塔拉罗米切斯马尔内菲感染呈现为肺腔结节:一个病例报告
Xiaoying Qin1, Jun Zou2, Zhiwen Jiang3
1Guangxi Medical University, Nanning, 530021, China.
BMC infectious diseases
|October 14, 2025
概括
艾滋病毒患者的塔拉罗米科斯可以呈现为罕见的腔腔肺结节. 通过微生物学检查及时诊断对于有效治疗和预防疾病进展至关重要.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 塔拉罗米科斯是一种危及生命的真菌感染,在亚洲的高级HIV患者中很常见.
- 肺部干扰是典型的,通常在CT扫描上呈现为分散的网状或地面玻璃变化.
- 腔腔结节在HIV阳性个体中是一种不常见的表现,可能会延迟诊断.
研究的目的:
- 报告一种罕见的散布型塔拉罗米科斯病例,该病例在感染艾滋病毒的患者中呈现出空腔肺结节.
- 强调微生物学确认在诊断异常呈现的塔拉罗菌根病时的重要性.
主要方法:
- 一个46岁的女性未经治疗的艾滋病毒和长期发烧的案例报告.
- 胸部CT显示了一个腔腔结节,最初怀疑是瘤.
- 通过CT指导肺活检证实诊断,显示了肺和骨髓中的真菌子和Talaromyces marneffei的阳性培养物.
主要成果:
- 这名患者被诊断出患有扩散型 talaromycosis.
- 首次使用安波特乙治疗导致显著的临床改善和肺结节的消失.
- 随访一年的伊特拉可纳没有显示疾病复发.
结论:
- 肺部 talaromycosis 可以表现为腔腔结节性病变.
- 微生物学检查对于准确及及时诊断塔拉罗米科सिस至关重要,特别是在异常呈现时.
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