多发性硬化症患者的睡眠障碍和相关因素:伊朗的横截面研究
Arshia Ghalamkari1, Yousef Mokary2,3, Saba Naghavi4,5
1Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
BMC neurology
|October 14, 2025
概括
睡眠障碍包括不安腿综合征,失眠和阻塞性睡眠呼吸暂停在伊朗多发性硬化症患者中很常见. 年龄和性别影响阻塞性睡眠呼吸暂停风险,而残疾状况影响不安腿综合征.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
背景情况:
- 在患有多发性硬化症 (PwMS) 的人中,睡眠障碍经常被低估,因为人们专注于身体症状.
- 这项研究探讨了伊朗PwMS中睡眠障碍的患病率和促成因素.
研究的目的:
- 调查伊朗多发性硬化症患者的睡眠障碍的患病率,包括不安腿综合征 (RLS),失眠和阻塞性睡眠呼吸暂停 (OSA).
- 确定与这些睡眠障碍相关的人口和临床因素.
主要方法:
- 在伊朗,对796名患有多发性硬化症的人进行了一项横截面研究.
- 经过验证的问卷,包括国际不安腿综合征研究小组,STOP-Bang,柏林和失眠严重程度指数,用于评估睡眠障碍.
主要成果:
- 在12.69% (STOP-Bang) 和11.56% (柏林) 的参与者中发现了高风险的OSA.
- 失眠 (49.5%) 和严重的RLS (48.87%) 非常普遍.
- 年龄和性别与OSA风险有显著的关联,而扩展残疾状态量表 (EDSS) 与RLS严重程度相关.
结论:
- 像RLS,失眠和OSA这样的睡眠障碍在伊朗PwMS中非常普遍.
- 医生应考虑EDSS用于RLS管理,并认识到年龄和性别对这一群体OSA风险的影响.
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