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葡萄糖皮质类药物在复发性异常性内肠置中的作用:一项回顾性队列研究
Jiyin Zhang1, Tingting Liu1, Dayong Wang1
1Department of Emergency Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nanlishi St, Xicheng District, Beijing, 100045, China.
葡萄糖皮质类药物显著降低了空气阴囊后儿童的异常性静脉吸收的短期复发. 这种治疗没有显著的不良影响,为治疗复发性内异常提供了一种安全的选择.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 临床治疗学 临床治疗学
- 医疗干预 医疗干预
背景情况:
- 异常性肠受是婴儿和儿童肠道阻塞的常见原因.
- 反复出现的静脉接发作是一个临床挑战,需要有效的管理策略.
- 葡萄糖皮质激素在减少后预防短期复发的作用仍然是研究领域.
研究的目的:
- 评估葡萄糖皮质类药物的有效性,降低儿科患者异常性静脉接的短期复发率.
- 评估该患者群体中葡萄糖皮质激素的安全性.
主要方法:
- 一项回顾性队列研究包括在2015年1月至2024年1月期间接受治疗的患有复发性异常性肠接的儿童.
- 经过光学引导气囊 (FGAE) 成功治疗的患者被分为干预 (糖皮质体) 和对照组.
- 分析了短期复发率 (14天内),延迟并发症和不良反应.
主要成果:
- 总共有183名儿科患者被纳入最终分析.
- 在葡萄糖皮质醇干预组 (18.6%) 的复发率明显低于对照组 (46.6%) (P=0.001).
- 在葡萄糖皮质醇治疗中没有观察到显著的延迟并发症或不良反应.
结论:
- 葡萄糖皮质类药物显示出显著的有效性,减少了儿童的异常性内接收的短期复发.
- 在这种情况下,使用葡萄糖皮质激素似乎是安全的,没有报告明显的不良影响.
- 这一发现支持葡萄糖皮质类药物作为一种有益的辅助疗法,用于治疗复发性儿科内肠.
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