针对与白内障同时存在的多发性糖尿病视网膜病变的双阶段发酵和帕斯普拉纳视切除术的结果:一项比较研究
Qian Wang1,2, Chunli Liu1,2, Gongqiang Yuan3,4
1Eye Institute of Shandong First Medical University, Eye Hospital of Shandong First Medical University(Shandong Eye Hospital), Jinan, China.
BMC ophthalmology
|October 14, 2025
概括
与联合手术相比,多发性糖尿病视网膜病变和白内障的连续手术可以减少早期的炎症. 这两种方法都提供了类似的长期视觉结果,强调个性化的患者护理.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜外科手术 视网膜外科手术
- 白内障手术 手术 白内障手术
背景情况:
- 糖尿病视网膜病变 (DR) 和白内障经常并存,使治疗复杂化.
- 手术管理需要仔细考虑时间和方法,以优化结果.
研究的目的:
- 为了比较顺序与联合手术方法的疗效和安全性,眼睛与共存的多发性糖尿病视网膜病变 (PDR) 和白内障.
主要方法:
- 对97个患有PDR和白内障的眼睛进行了回顾性分析,这些眼睛接受了连续或联合手术.
- 序列性手术涉及初始的药物治疗与化/IOL,随后的一周后,帕斯普拉纳视切除术 (PPV).
- 组合手术涉及初始药物治疗,然后一周后同时进行PPV,发酵乳化和IOL植入.
主要成果:
- 相比于联合手术 (P <0.05),连续手术显示早期术后前腔 (AC) 炎症 (细胞≥2+,纤维性排泄,后部突) 的发生率显著降低 (P <0.05).
- 这两组从手术前到最后的随访期间,最佳校正视敏度 (BCVA) 显著改善 (P <0.05).
- 在顺序和联合手术组之间没有观察到最终BCVA的统计学上显著差异 (P > 0.05).
结论:
- 连续和联合的手术策略都有效治疗PDR与同时出现的白内障.
- 序列性手术与早期术后炎症反应的减少有关.
- 两种方法之间的长期视觉结果是可比的,支持基于患者因素和外科医生偏好的个性化治疗决策.
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