在第三手术中,特拉马多尔与局部麻醉相结合,用于术后疼痛
İbrahim Murat Afat1, Onur Gönül2, Tülin Satılmış3
1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Marmara University, Istanbul, Turkey. muratafat2@gmail.com.
BMC oral health
|October 14, 2025
概括
结合局部麻醉剂和特拉马多尔,在第三手术后显著降低了术后疼痛和止痛药的消耗. 这种有效的疼痛管理策略增强了患者的康复,并提出了更广泛的临床应用.
科学领域:
- 在口腔外科手术.
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术后疼痛管理是口腔外科手术的一个重大挑战.
- 特拉马多尔具有全身和局部止痛作用,与局部麻醉剂有效.
研究的目的:
- 评估局部麻醉剂与特拉马多尔结合在第三手术后减轻疼痛和减少止痛需求时的疗效.
- 评估这种组合对患者康复和止痛药使用的影响.
主要方法:
- 一个随机的双盲试验比较了两个组:特拉马多尔和阿尔蒂卡因与上腺素 (LT组) 与单独使用上腺素的阿尔蒂卡因 (LA组).
- 包括60名接受了受影响的第三手术的患者.
- 术后疼痛使用视觉模拟量表 (VAS) 进行测量,次要结局包括首次止痛剂的时间和在48小时内消耗的总止痛剂量.
主要成果:
- 与对照组 (LA) 相比,在手术后1,2和6小时,特拉马多尔-利多卡因组 (LT) 报告的VAS疼痛得分明显较低.
- 长期治疗组的患者在48小时内出现了延迟的首次止痛药摄入 (5.2小时与2.0小时相比),并且服用的止痛药减少 (1.8小时与3.6小时相比).
- 虽然在LT组在4小时后注意到VAS得分的暂时增加,但不良影响是最小的,并且在不同组之间可比.
结论:
- 局部麻醉剂与特拉马多尔的结合有效地减少了第三手术后的术后疼痛和止痛药的使用.
- 这种方法增强了患者的康复,并表明在疼痛管理策略中更广泛应用的潜力.
- 需要进一步的研究来探索这种止痛药组合的更广泛的临床实用性.
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