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风险因素和预测模型为淋巴结转移后面的右回复性喉神经在乳头甲状腺癌的淋巴结转移

Xiaowen Fang¹, Jihao Qin², Chenxi Liang¹

¹Department of Gastrointestinal and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Guangxi18 Zhuang Autonomous Region, Nanning, 530021, P.R. China.

World journal of surgical oncology

|October 15, 2025

概括

这项研究确定了在乳头甲状腺癌 (PTC) 中右喉神经后部淋巴结转移的关键风险因素. 一个经过验证的预测模型有助于进行手术规划,以获得更好的患者结果.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
内分泌学在内分泌学.

背景情况:

在乳头甲状腺癌 (PTC) 中,右侧复发性喉神经 (LN-prRLN) 以后的淋巴结转移会带来外科挑战.
这种转移与疾病复发的增加有关.
深度解剖位置使手术干预复杂化.

研究的目的:

在PTC中确定LN-prRLN转移的独立风险因素.
开发和验证临床决策的预测模型.
改善潜在LN-prRLN参与的PTC患者的手术规划.

主要方法:

对341名接受LN-prRLN剖析的PTC患者进行了回顾性分析.
转移阳性和阴性组之间的临床病理学特征的比较.
后勤回归用于识别风险因素并构建名图;使用ROC曲线,校准图和DCA的模型验证.

主要成果:

男性性别,较大的瘤直径,多焦点性,侧侧淋巴结转移和甲状腺外延伸是LN-prRLN转移的独立风险因素.
命名图表显示出极好的区别 (AUC:0.889培训,0.858验证).
该模型显示了良好的校准和强大的临床实用性.

结论:

在PTC中确定了LN-prRLN转移的新型独立风险因素.
开发的预测模型在临床应用中表现出令人满意的性能.
促进个性化手术规划,以优化治疗疗效并最大限度地降低手术风险.

关键词:

中枢淋巴结的中枢淋巴结.淋巴结背后的右侧循环喉神经的淋巴结.预测转移的转移.这个名字是名ogramogram.乳头甲状腺癌是一种乳头甲状腺癌.

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