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Updated: Jan 15, 2026

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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使用蛋白质语言模型推进病毒性因子预测

Yitong Liu1, Xin Cao1, Jiani Li1

  • 1School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of Life and Health, Hainan University, Haikou, 570228, Hainan, China.

BMC biology
|October 15, 2025
PubMed
概括

这项研究引入了pLM4VF,这是一个用于预测细菌毒性因子 (VFs) 的新框架,无论是阳性细菌还是阴性细菌. pLM4VF显著提高了预测准确度,为了解细菌疾病和开发新治疗方法提供了宝贵的工具.

关键词:
细菌感染是一种细菌感染.机器学习是机器学习.蛋白质语言模型的模型堆叠策略 堆叠策略病毒性因素是病毒性因素.

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