生命必需8指标与痛风风险之间的反向和非线性关系:一个横截面研究
Yiheng Cheng1, Yi Feng1, Moran Huang1
1Department of Urology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
Medicine
|October 15, 2025
概括
使用生命必需8 (LE8) 度量来改善心血管健康与患痛风的风险降低有关. 较高的LE8得分显著降低了痛风的患病率,这表明最佳心脏健康的保护作用.
科学领域:
- 心血管健康 心血管健康
- 类风湿病学 类风湿病学
- 公共卫生 公共卫生
背景情况:
- 痛风是一种与心血管疾病相关的流行炎症性关节炎.
- 生活必需品8 (LE8) 是对心血管健康的综合测量.
- 了解心血管健康和痛风风险之间的联系对于预防策略至关重要.
研究的目的:
- 为了研究生命的基本8 (LE8) 评分和美国成年人中痛风的流行率之间的联系.
- 为了确定更好的心血管健康,以LE8测量,是否与患上痛风的风险降低有关.
主要方法:
- 分析国家健康和营养检查调查 (NHANES) 2005-2018年的数据.
- 使用后勤回归模型来评估LE8分数和痛风风险之间的关系.
- 进行了调整分析,灵敏度分析,四分位数和子组分析.
主要成果:
- 与没有痛风的人相比,痛风患者的LE8得分 (58.28比67.06) 显著较低.
- 较高的LE8分数与痛风风险相反相关;10分的增加与21%的风险降低相关.
- 与最低四分位数相比,最高LE8四分位数的痛风风险降低了54%,表明了剂量-反应关系.
结论:
- 最佳的心血管健康,反映在更高的LE8得分,显著与痛风的流行率降低有关.
- 遵守推的心血管健康指标可能是减轻痛风负担的潜在策略.
- 这些发现强调了心血管健康和诸如痛风等代谢疾病的相互联系.
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