产前的SARS-CoV-2感染会加剧产后的下尿道症状吗? 一个多中心的回顾性队列研究
Yu Han Lyu1, Min Li2, Hui Qing Yao3
1Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Beijing 100730, China;Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Biomedical and environmental sciences : BES
|October 15, 2025
概括
产前COVID-19感染并没有增加产后泌尿症状. 然而,严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染独立影响了盆地肌肉活动,表明了潜在的神经肌肉影响.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 众所周知,冠状病毒疾病2019 (COVID-19) 会导致疲劳和炼后的不适.
- 严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染在产后期间对下尿道症状 (LUTS) 的影响尚不清楚.
研究的目的:
- 为了调查产前SARS-CoV-2感染与产后LUTS发生之间的关联.
- 评估产前SARS-CoV-2感染对盆地肌肉活动的影响.
主要方法:
- 一项多中心回顾性队列研究包括来自中国两个三级医院的3,652名参与者.
- 参与者被分为SARS-CoV-2感染者和未感染者.
- 用自我报告的症状和IIQ-7来评估LUTS,而通过电肌图测量骨盆底肌活动.
主要成果:
- 在感染和未感染组之间,没有发现LUTS患病率或严重程度 (IIQ-7分数) 的显著差异.
- 产前的SARS-CoV-2感染被确定为影响盆地肌肉电肌图学活性 (平均强力收缩幅度) 的独立因素.
- 这些对骨盆底肌肉的影响,不论是如何输送,都被观察到.
结论:
- 产前SARS-CoV-2感染与产后LUTS的风险增加没有显著关联.
- 然而,SARS-CoV-2感染独立地改变了盆地肌肉电肌图学活动.
- 这表明病毒对骨盆地功能有潜在的神经肌肉影响.
相关概念视频
01:25Urinary Tract Infection II: Pathophysiology
567
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
567
01:30Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
252
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
252
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
372
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
372
01:26Urine Studies II: Urine Culture and Sensitivity Test
850
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
850
01:17Urinary Tract Infection IV: Nursing Management
434
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
434
01:26Urinary Tract Infection I: Introduction
534
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
534