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Updated: Jan 15, 2026

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肝星状细胞细胞外囊中的普罗林诱导了血小板依赖的血栓的形成和释放的profibroticTGF-β

Rui Chen1, Emily Huang2, Xianfang Wu3

  • 1Department of Cardiovascular & Metabolic Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, Ohio, USA.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|October 15, 2025
PubMed
概括

肝星细胞 (HSCs) 释放细胞外囊泡 (EVs),通过prorenin激活血小板,从而启动肝纤维化. 这种新发现的途径突出显示了肝病进展中的HSC-EVs和prorenin.

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