流体评估评分工具 (FAST):为重症儿科患者开发一种新的流体评估评分工具-试点研究
Mohammed Salameh1, Pranali Awadhare2, Jennifer Joiner3
1Critical Care Medicine, University of Texas Southwestern Medical Center, Dallas, USA.
Cureus
|October 15, 2025
概括
一个新的流体评估评分工具 (FAST) 有助于评估重症儿童的流体过载. 3或更高的FAST分数表明临床实用性,用于识别儿科重症监护病房的液体过载.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 关键护理神经病学 关键护理神经病学
- 临床评估工具 临床评估工具
背景情况:
- 监测液体平衡在儿科重症监护室 (PICU) 中至关重要,但具有挑战性.
- 现有的流体评估方法往往是不可靠的或不切实际的,对于重症儿童.
- 需要复合得分或临床算法来全面评估儿科流体状况.
研究的目的:
- 开发和验证一种新的流体评估评分工具 (FAST),用于PICU患者的临床使用.
- 用复合评分系统评估重症儿童的流体状况.
主要方法:
- 一项试点研究包括了需要机械通风,异型药物,利尿剂或置换疗法的重症儿科患者 (0-21岁).
- 开发了一个10分的FAST,分数参数如 fontanelles,眼睛,肝脏检查,每日体重变化,液体平衡,尿液输出和实验室值.
- 通过ICON®监视器测量的胸液含量 (TFC) 作为参考标准;ROC分析确定了FAST切割点.
主要成果:
- 该研究分析了来自32名儿科患者的118次遭遇;66%的TFC显示高,表明液体过载.
- 快速评分≥3 (灵敏度92%,特异性68%) 和≥4 (灵敏度80%,特异性80%) 预测高TFC.
- 交叉验证显示FAST≥3 (AUC=0.79) 和FAST≥4 (AUC=0.78) 的性能相似;没有观察到患者结局的显著差异.
结论:
- 开发的FAST提供了一种实用的方法,用于评估重症儿科患者的液体过载.
- 快速评分≥3与TFC定义的液体过载有关,表明潜在的临床效用.
- 需要进一步的多中心研究来验证FAST并评估其对患者结果的影响.
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