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双边甲醇诱导的视神经病变在手洗手剂摄入后发生
Caroline Simon Sherman1, Julius T Oatts1,2, Danielle Sarlo1,2
1Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA, USA.
American journal of ophthalmology case reports
|October 15, 2025
概括
一名患有自闭症谱系障碍 (ASD) 和皮卡的儿童在摄入手洗手剂后发展出甲醇诱导的视神经病变. 早期识别和治疗,就像血液透析一样,对于脆弱儿科患者的视觉恢复至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 毒理学 毒理学 毒理学
- 儿科 儿科 儿科
背景情况:
- 患有自闭症谱系障碍 (ASD) 和皮卡的儿童患有有毒物摄入的风险增加.
- 含有甲醇的手消毒剂具有明显的视神经损伤风险.
研究的目的:
- 报告一个患有ASD的儿科患者中甲醇诱导的视神经病变病例.
- 强调早期诊断和治疗对视觉保存的重要性.
主要方法:
- 一个案例报告,一名11岁的女性患有自闭症和皮卡,她摄入了手洗手剂.
- 临床检查包括后视镜和光学连贯性断层扫描 (OCT).
- 在怀疑甲醇毒性的情况下启动血液透析.
主要成果:
- 患者出现双边"斑点"视力和头.
- 基底镜检查显示了轻微的双边光盘胀.
- 经过测试,OCT显示了视网膜神经纤维层 (RNFL) 的全球加厚.
结论:
- 摄入甲醇可以导致儿童严重的视神经病变,特别是那些患有ASD和pica的儿童.
- 及时识别症状并启动治疗,如血液透析,对于潜在的视力恢复至关重要.
- 在这种脆弱人群中,高临床怀疑对于管理有毒视神经病变至关重要.
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