在死角性肠球炎的第二次外科手术中,印ocyanine绿色光:增强外科医生的感知能力
Antonia Maximina Pfennigs1, Manuel Besendörfer2, Sonja Diez2
1Clinic for Pediatric Surgery and Traumatology, Florence Nightingale Hospital, Düsseldorf, Germany.
Frontiers in pediatrics
|October 15, 2025
概括
绿色氨酸 (ICG) 光成像可靠地评估在死性肠球炎 (NEC) 手术期间的肠道活力. 这种实时方法改善了对新生儿肠切除的客观边缘定义,提高了外科手术的结果.
科学领域:
- 新生儿手术 新生儿手术
- 胃肠病学 胃肠病学
- 医疗成像医学成像
背景情况:
- 过早出生婴儿的死性肠球炎 (NEC) 是由肠道 perfusion 问题驱动的,需要手术切除死组织.
- 目前的外科实践依赖于视觉检查来确定肠道活力和切除边缘,缺乏客观标准.
- 印ocyanine绿色 (ICG) 光成像为客观评估肠道输液和活力的潜在实时解决方案.
研究的目的:
- 评估ICG光成像在确定NEC手术期间死亡边缘的可靠性.
- 将基于ICG的肠道活力的评估与传统的外科判断和组织病理学进行比较.
- 研究ICG在指导NEC肠道救援手术决策中的实用性.
主要方法:
- 一项前性研究,涉及早产新生儿接受为确诊的NEC进行手术.
- 在暴露肠束后,进行ICG光成像 (0.04-0.7 mg/kg) 的手术内应用.
- 将ICG输液可视化与外科医生对肠道活力的评估进行比较,然后与组织病理学相关联.
主要成果:
- 在4/6名患者中,ICG确定了非重要的肠道区域,导致边缘<1毫米的切除,由组织学证实.
- 在2/6名患者中,ICG证实了完整的肠道亡,支持了息治疗决策.
- 在2/6名患者中,ICG发现与临床判断相矛盾,ICG准确地识别了由组织病理学证实的亡.
结论:
- 在NEC手术期间,ICG光成像是一种有用和可靠的工具,可以对血液 perfusion 和肠道活力进行客观化.
- 这种方法为外科医生在确定切除边缘方面的经验增加了客观性.
- ICG成像可以改善NEC新生儿的手术决策和结果.
更多相关视频
相关概念视频
Endoscopic Studies II: Thoracocentesis
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Inflammatory Bowel Disease V: Surgical Management
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
Endoscopic Procedures II: Colonoscopy
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Endoscopic Procedures III: Video Capsule Endoscopy
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures V: ERCP
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...


