饮食纤维摄入量与认知功能之间的关联:炎症标志物的调解作用
Kaiyun Yan1, Xinshuo Wang1, Fengdan Wang1
1School of Public Health, Jilin University, Changchun, China.
Frontiers in nutrition
|October 15, 2025
概括
食纤维摄入量与更好的认知功能和较低的炎症有关. 专与性酸酶比率 (AAPR) 调解了这种积极影响,突出了其在大脑健康中的作用.
科学领域:
- 营养科学 营养科学
- 神经科学是一个神经科学.
- 生物标志物 生物标志物
背景情况:
- 认知障碍越来越令人担忧,特别是在阿尔茨海默氏症等神经退行性疾病中.
- 饮食因素,包括纤维摄入量和炎症过程都与认知健康有关.
- 新的炎症标志物需要进一步研究它们在认知功能中的作用.
研究的目的:
- 研究饮食纤维摄入量,新型炎症标志物和认知功能之间的关联.
- 探索炎症标志物,特别是AAPR,NAR和SIRI在食纤维和认知之间关系中的调解作用.
主要方法:
- 利用了2011-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 通过使用DSST,CERAD-WL,CERAD-DR和AFT等测试来评估认知功能.
- 采用线性回归和调解分析来检查食纤维,炎症标志物 (AAPR,NAR,SIRI) 和认知表现之间的关系.
主要成果:
- 食纤维摄入量与认知测试 (CERAD-WL,AFT) 和炎症标志物 (AAPR,NAR,SIRI) 有显著的关联.
- 专与性酸酶比率 (AAPR) 与单词学习和动物流利性有积极联系.
- AAPR显著调解了食纤维摄入量与动物流利性测试表现之间的积极关联,占17.88%.
结论:
- 食纤维摄入量,炎症标志物和认知功能是相互关联的.
- 专与性酸酶比率 (AAPR) 起到调解作用,将食纤维摄入量与改善的认知功能联系起来.
- 研究结果表明,潜在的营养和炎症途径会影响认知健康.
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