炎症性肠病和整体关节整形术后的不良结果:系统性审查和元分析
Mohammad-Taha Pahlevan-Fallahy1, Farhad Shaker1, Amir-Mohammad Asgari2
1School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
JB & JS open access
|October 15, 2025
概括
患有炎症性肠病 (IBD) 的患者在全关节关节整形术 (TJA) 后面临更高的术后并发症风险,包括感染和血栓. 建议对这个群体进行个性化管理.
科学领域:
- 整形外科手术 整形外科手术
- 胃肠病学 胃肠病学
- 系统性炎症研究 系统性炎症研究
背景情况:
- 炎症性肠病 (IBD) 与全身炎症有关,可能影响手术结果.
- 整体关节整形术 (TJA) 越来越多地在老年IBD患者中进行.
- 这项研究调查了IBD和TJA后的术后并发症之间的关联.
研究的目的:
- 评估在接受TJA的IBD患者中术后并发症的风险.
- 在关节置换手术的背景下,识别与IBD相关的特定并发症.
主要方法:
- 研究的系统审查,包括接受TJA的IBD和无IBD患者.
- 在PubMed,Scopus,Web of Science和Embase数据库中进行了搜索.
- 使用随机效应模型进行的元分析,具有95%的置信区间.
主要成果:
- 分析了14项涉及超过260万患者的研究.
- IBD与周围假肢关节感染 (PJI),再入院,肺炎,血栓栓塞事件 (PTE,VTE,DVT),,C. difficile感染,心肌梗塞 (MI),脑血管事故 (CVA),尿路感染 (UTI),败血症,呼吸系统衰竭,修复手术,周围假肢骨折,伤口并发症和植入物并发症的风险增加有显著关联.
- 住院时间略长;死亡率和非家庭出院率没有显著差异.
结论:
- 接受TJA的IBD患者面临特定术后并发症的风险增加,特别是感染,血栓栓塞事件和修复手术.
- 这些发现强调了对接受TJA的IBD患者进行个性化管理策略的需要.
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