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病例报告:CHD4中的新突变引发了带有骨转移的隐性乳腺癌

Hang Dong1, Jingtong Zhao2, Boyin Zhang3

  • 1Department of Traumatic Orthopedics, Jilin University China-Japan Union Hospital, Changchun, China.

Frontiers in oncology
|October 15, 2025
PubMed
概括

在转移性乳腺癌中发现了一种新的CHD4基因突变,破坏了表观遗传调节,并可能增强基因激活. 这一发现可能会将受损的染色质重塑与癌症进展联系起来.

关键词:
这是一种CHD4突变.现在的NuRD复合体是什么?骨转移发生在骨髓中.表观遗传修饰是一种表观遗传修饰.隐藏的乳腺癌 隐藏的乳腺癌

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