Penicillium hordei的酸化沉Bacillus subtilis的脂,以逃避抑制的作用
Manca Vertot1, Morten D Schostag1, Aaron J C Andersen1
1Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2100 Kongens Lyngby, Denmark.
ISME communications
|October 15, 2025
概括
菌类使用酸化来防御细菌,通过沉细菌性脂来防御细菌. 这种相互作用促进了土壤中稳定的植物有益的微生物群落.
科学领域:
- 微生物学 微生物学
- 植物病理学 植物病理学
- 生态生态学 生态生态学
背景情况:
- 有益细菌和真菌之间的相互作用对生态系统健康至关重要,但人们对其了解甚少.
- 植物有益的微生物,如Penicillium和Bacillus,可以抑制病原体并促进植物生长.
研究的目的:
- 为了研究 Penicillium hordei 和 Bacillus subtilis* 之间的相互作用中介的二次代谢物.
- 阐明共同培养期间观察到的脂沉背后的机制.
主要方法:
- 在上共同培养P. hordei和B. subtilis.
- 代谢分析以确定关键化合物.
- 评估真菌代谢物对细菌脂酸生产和抗真菌活性的影响.
主要成果:
- 共同培养诱导的 *B. subtilis* 脂的沉,可视化为白线.
- 菌的陆地酸生产被*B. subtilis*增强,导致脂沉和失活.
- 陆地酸诱导的酸化降低了抗真菌的皮帕斯塔丁,允许真菌过度生长.
- 白线现象在分泌类似酸的相关真菌中得到保留,而陆地酸则具有普遍作用.
结论:
- 酸化是一种真菌防御策略,促进与敌对细菌的共存.
- 这种机制有助于树根球微生物群落的稳定.
- 这些发现为土壤生态系统的王国间通信提供了新的见解.
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