生命必需8分和心力衰竭之间的关联:来自NHANES (2007-2020) 的见解
Houde Duo1, Shifeng Zhao1, Yuhang Zhao1
1The Sixth Clinical School of Medicine, Capital Medical University, 100013 Beijing, China.
Reviews in cardiovascular medicine
|October 15, 2025
概括
高生活的基本8 (LE8) 评分与美国人的心力衰竭 (HF) 患病率较低有关. 这表明LE8指标可以帮助识别公共卫生中高风险人群.
科学领域:
- 心血管健康 心血管健康
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 由于高发病率,死亡率和经济成本,心力衰竭 (HF) 构成了重大的公共卫生挑战.
- 早期识别和预防可修改的风险因素对于降低HF患病率至关重要.
- 美国心脏协会的生命必需8 (LE8) 指标提供了一个全面的心血管健康评估框架.
研究的目的:
- 调查LE8指标与美国人口中HF患病率之间的关联.
- 确定LE8指标是否可以帮助公共卫生倡议的高温风险分层.
- 探索LE8定义的心血管健康与心力衰竭的发生之间的关系.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2007-2020) 的横截面分析.
- 包括年龄≥20岁的参与者,具有完整的HF和LE8指标数据.
- 使用多重后勤回归,子组分析,相互作用测试,平滑曲线拟合和ROC曲线分析.
主要成果:
- 在LE8得分和HF患病率之间观察到显著的逆剂量反应关系.
- 与得分最低的人 (OR=0.30,P<0.01) 相比,LE8得分最高的个体患上HF的患病率降低了70%.
- 身体活动,尼古丁暴露,睡眠健康,BMI和血葡萄糖独立地与HF患病率有关.
结论:
- 较高的LE8得分与心力衰竭的发病率降低密切相关.
- 在公共卫生环境中,LE8指标显示出作为一种有价值的工具来识别高风险人群的潜在潜力.
- 通过LE8成分改善心血管健康可能是预防心力衰竭的关键.
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