一项关于在患有喘的儿童中建立持续性ICS药物坚持行为模型的研究
Li Yan1, Rong Guo2, Liping Wu3
1Department of Pediatric Intensive Care Unit, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Engineering Research Center of Stem Cell Therapy, Chongqing, China.
Frontiers in public health
|October 15, 2025
概括
一个新的模型确定了影响喘儿童服药的关键因素. 行为意图,药物信念和知识对于持续坚持吸入性皮质类固醇 (ICS) 非常重要.
科学领域:
- 儿科肺病学 儿科肺病学
- 健康行为研究 研究健康行为研究
- 心理学 心理学 心理学
背景情况:
- 喘是一种慢性呼吸道疾病,影响全球数百万儿童.
- 吸入性皮质类固醇 (ICS) 是喘管理的基石,但遵守可能是具有挑战性的.
- 患有喘的儿童不够坚持ICS导致喘恶化和医疗利用率增加.
研究的目的:
- 开发和验证一个持续的坚持性行为模型,用于吸入性皮质类固醇 (ICS) 药物在患有喘的儿童.
- 确定影响该群体药物坚持行为的关键因素.
- 为旨在改善ICS遵守的干预提供一个框架.
主要方法:
- 文献审查和半结构面试,以开发一个问卷项目库.
- 专家咨询 (两轮) 改进和验证影响因子规模.
- 对370名患有喘的儿童进行了调查,使用开发的尺度和结构方程建模.
主要成果:
- 最终的尺度包括5个一级和23个二级项目,显示出良好的可靠性 (克朗巴赫的α=0.925).
- 结构方程建模显示,行为意图 (0.522),药物知识 (0.193) 和药物信念 (0.181) 对ICS坚持有直接显著影响.
- 通过规范信念 (0.161) 和自我有效性 (0.140) 观察到间接影响,该模型解释了46%的坚持差异.
结论:
- 基于健康信念理论开发的模型有效地解释了喘儿童的ICS药物坚持.
- 行为意图成为坚持最强的预测因素,其次是药物信念和知识.
- 这些发现为设计有针对性的干预措施提供了有价值的见解,以改善儿童喘管理的坚持.
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