局部类固醇戒断管理的初步共识:德尔菲研究
Sarah Kamsiah Zemlok1,2, Mykayla Sandler2,3, JiaDe Yu2
1From the University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Dermatitis : contact, atopic, occupational, drug
|October 15, 2025
概括
缺乏局部类固醇戒断 (TSW) 管理指南. 专家们就停止局部/全身类固醇,心理社会支持和杜比卢马布作为TSW的第一线治疗达成共识.
科学领域:
- 皮肤病学 皮肤病学
- 临床实践指南 临床实践指南
背景情况:
- 局部类固醇戒断 (TSW) 是一种与长期局部皮质类固醇使用相关的新出现的疾病.
- 目前对TSW缺乏管理指南,需要专家协商一致来确定临床方向.
研究的目的:
- 建立局部类固醇戒断 (TSW) 的初步专家共识和管理准则.
- 利用修改后的Delphi共识方法来制定基于证据的建议.
主要方法:
- 一个由21名医生和患者倡导者组成的小组评估了72种管理策略.
- 为了达成共识,进行了两轮调查 (≥70%的同意/不同意).
主要成果:
- 专家们达成共识的12个关键结果,强调停用皮质类固醇和心理社会支持.
- 杜皮卢马布被确定为基于共识的TSW的一线全身疗法.
结论:
- 通过专家的共识,TSW的初始管理准则已建立.
- 这些指导方针为TSW治疗提供了一个框架,等待进一步的研究和基于证据的治疗方法.
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