在使用口水治疗牙过敏症的随机临床试验中遵守CONSORT声明
Lauro Taques Neto1, Letícia Maira Wambier2, Ana Cláudia Rodrigues Chibinski2
1Department of Dentistry, State University of Ponta Grossa, General Carlos Cavalcanti Avenue, 4748, Uvaranas, Ponta Grossa, Paraná, 84030-900, Brazil. lauroneto15@hotmail.com.
The Saudi dental journal
|October 15, 2025
概括
这项研究评估了随机临床试验 (RCT) 对于牙过敏 (DH) 的脱敏化口水. 虽然大多数研究的偏差风险较低,但未能完全遵守CONSORT报告准则.
科学领域:
- 牙科 牙科是指牙科的专业.
- 临床试验方法论 临床试验方法论
背景情况:
- 该CONSORT声明指导随机临床试验 (RCT) 的报告.
- 许多RCT评估牙过敏性 (DH) 的脱敏口水,但其通过CONSORT指南的质量未被评估.
研究的目的:
- 评估RCT对DH脱敏口水的RCT与CONSORT指南的遵守情况.
- 为了评估这些包含的RCT中偏差的风险.
主要方法:
- 在多个数据库 (科克兰图书馆,MEDLINE,Embase等) 中进行系统搜索. 从2024年8月到10月.
- 通过使用特定的CONSORT坚持工具和Cochrane偏差风险工具评估36个选定的RCT 2.
主要成果:
- 平均CONSORT分数为23.3/32,干预和结果报告良好,但缺乏设置和协议注册.
- 根据期刊和出版日期,观察到CONSORT得分的显著差异.
- 14项研究显示偏差风险低,2项没有明确风险,没有高风险.
结论:
- 对DH脱敏口水的RCT显示出良好的方法质量,偏差风险低.
- 在这个领域,完全遵守CONSORT报告标准并未始终实现,这表明有改进的余地.
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