紧急部门的COVID-19增强剂疫苗信息:一个集群随机临床试验
Melanie F Molina1, Stephanie A Eucker2, Kristin L Rising3,4
1Department of Emergency Medicine, University of California, San Francisco.
JAMA network open
|October 15, 2025
概括
量身定制的消息和简单的询问并没有显著提高紧急部门更新的COVID-19疫苗接种率. 然而,疫苗的可用性对接种产生了积极的影响,突出显示了疫苗的配送方便性.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 患者接受更新的COVID-19疫苗对于缓解严重疾病至关重要,但目前的疫苗接种率仍然低于最佳水平.
- 由于患者数量很高,急诊室 (EDs) 是增加疫苗注射的潜在环境.
研究的目的:
- 评估定制消息或简单的关于疫苗接受的询问是否会增加成年ED患者在30天内接受更新的COVID-19疫苗.
- 为了比较两个干预措施 (定制消息和调查) 与增加疫苗接种率的通常护理的有效性.
主要方法:
- 一个三臂,集群随机临床试验,涉及852名成年ED患者在美国四个州的6个ED.
- 干预包括量身定制的消息加上调查 (干预M),仅仅是调查 (干预Q) 或通常的护理 (控制).
- 主要结果是30天内更新的COVID-19疫苗接种,通过电子健康记录和电话评估.
主要成果:
- 无论是量身定制的消息还是简单的询问,都没有显著增加30天的疫苗接种量,而不是通常的护理.
- 然而,在可用更新的COVID-19疫苗的地点,干预M与对照组 (3.3%) 相比,显示了显著更高的吸收率 (9.8%).
- 疫苗的可用性似乎是一个效果修饰因素,这表明它在疫苗交付中的重要性.
结论:
- 量身定制的消息传递和简单的询问本身不足以显著增加在ED环境中更新的COVID-19疫苗的接种率.
- 这些发现强调了疫苗可用性,方便性和机会在推动疫苗接种方面的关键作用.
- 未来的战略应该集中在将疫苗管理无地整合到医疗保健中.
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