牛皮在童年或成年时的发病是否会影响心血管并发症?
Leyla Baykal Selçuk1, Esra Adişen2, Yusuf C Edek2
1Department of Dermatology, School of Medicine, Karadeniz Techinical University, Trabzon, Türkiye - lb_leyla@hotmail.com.
Italian journal of dermatology and venereology
|October 15, 2025
概括
儿童发病的牛皮 (COP) 患者表现出类似的代谢综合征率,但与成人发病的牛皮 (AOP) 相比,肥胖的发病时间较早. 早期,积极的治疗对于管理牛皮患者的并发症至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
背景情况:
- 牛皮是一种慢性炎症性疾病,与心血管和代谢问题有关.
- 童年发病的牛皮 (COP) 可能会影响长期并发症的发展.
- 了解这些联系对于患者管理至关重要.
研究的目的:
- 为了检查童年发病的牛皮和成人心血管/代谢并发症之间的相关性.
- 专注于30-50岁的患者,以评估长期影响.
主要方法:
- 一个横截面,多中心研究1922年牛皮患者.
- 收集有关人口统计,疾病,并发病,实验室和治疗的数据.
- 使用后勤回归来识别伴随疾病的相关因素.
主要成果:
- 34.5%的患者在18岁之前出现了牛皮.
- 代谢综合征的患病率和发病年龄在儿童发病的牛皮 (COP) 和成人发病的牛皮 (AOP) 组之间是相似的.
- 在COP中,肥胖的发病时间较早,但没有发现与牛皮发病的直接联系. 在AOP中,胆固醇,LDL和HOMA-IR的升高. COP患者早些时候使用了更多的系统/生物治疗方法.
结论:
- 代谢综合征的患病率和发病年龄在COP和AOP中是相似的.
- 在COP中肥胖的早期发作强调了儿童牛皮的体重管理的必要性.
- 针对皮肤和全身疾病的综合治疗对于长期的结果至关重要.
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