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STAG2 调节尿前体和膀癌中的多和分化

Youngrok Park1,2, Wanying Xu3,4, Tianyi Yang3,4

  • 1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia, United States of America.

PloS one
|October 15, 2025
PubMed
概括

对于细胞分裂至关重要的STAG2基因的突变与膀癌的发病有关. 不激活STAG2会破坏表观遗传调节,并阻碍细胞分化,从而提供新的治疗点.

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