定义高风险怀孕:对临床决定因素,并发症和不良分娩结果进行系统范围审查的协议
Xiali Yang1,2, Xin Wee Chen2, Philip R A Baker2,3,4,5
1School of Nursing, Ningxia Medical University, Ningxia, China.
PloS one
|October 15, 2025
概括
本系统性审查协议旨在确定高风险怀孕及其相关并发症的临床决定因素. 它将综合现有研究,以改善基于证据的管理和预防不良分娩结果.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 准确识别临床决定因素对于管理高风险怀孕和预防不良结果至关重要.
- 目前缺乏对区域分类系统,风险因素,并发症和高风险妊娠的不良分娩结果的系统综合.
- 这种差距阻碍了基于证据的规划和有针对性的干预.
研究的目的:
- 系统地识别和综合已发表的关于用于分类高风险妊娠状态的临床决定因素的研究.
- 评估确定研究中的偏差风险.
- 总结高风险妊娠状态及其并发症之间的关系.
主要方法:
- 将对多个文献数据库 (科克兰图书馆,科学网,CNKI,SCOPUS,PubMed-MEDLINE) 进行全面的搜索.
- 观察性研究将包括在没有语言限制的情况下.
- 将采用两阶段的选过程,包括独立的全文审查,偏见风险评估和两名审查员的数据提取.
- 将使用叙事综合来解决选择性出版偏见,遵守PRISMA-P指南.
主要成果:
- 该部分将在系统性审查完成后填写.
- 审查将确定关键的临床决定因素及其与高风险妊娠并发症的关联.
- 将总结现有文献中关于偏见风险的证据.
结论:
- 这一系统性审查将为高风险怀孕的临床决定因素提供全面的综合分析.
- 研究结果将为基于证据的临床实践提供信息,改善管理策略,并有助于减少不良分娩结果.
- 该研究协议已在PROSPERO (CRD420251026327) 登记.
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