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Updated: Jan 15, 2026

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肉瘤中生殖系致病变体的频率和临床特征:一个病例控制研究

Adela Rodriguez-Hernandez1,2,3, Miki Horiguchi4,5, Carolyn Horton6

  • 1Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, MA, United States.

Journal of the National Cancer Institute
|October 15, 2025
PubMed
概括

生殖系病原体变异在肉瘤患者中比对照患者更为常见,经常发现TP53和BRCA2等特定基因. 这凸显了在肉瘤护理中需要更广泛的生殖线检测的需要.

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