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CBTRUS统计报告:2018-2022年在美国诊断的初级大脑和其他中枢神经系统瘤
Mackenzie Price1, Christine Ann Pittman Ballard1,2, Julia R Benedetti1,2
1Central Brain Tumor Registry of the United States, Hinsdale, IL, U.S.A.
Neuro-oncology
|October 15, 2025
概括
美国中央脑瘤注册局每年报告每10万人有超过26例脑瘤和中枢神经系统瘤. 质母细胞瘤和脑膜瘤分别是最常见的恶性和非恶性瘤.
科学领域:
- 神经科学是一个神经科学.
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 美国中央脑瘤登记处 (CBTRUS) 是美国主要脑瘤和中枢神经系统 (CNS) 瘤人口数据的主要来源.
- 以前的报道提供了有价值的见解,但这项研究利用了最最新和最全面的数据集,涵盖了整个美国人口.
研究的目的:
- 呈现最最新的基于人口的统计数据,关于美国初级大脑和其他中枢神经系统瘤的发病率,死亡率和存活率.
- 分析这些瘤的人口变异和组织病理分布.
主要方法:
- 利用疾病控制和预防中心的癌症注册国家计划和国家癌症研究所的监测,流行病学和最终结果计划的汇总数据.
- 使用2000年美国标准人口计算每10万人口的年龄调整发病率.
- 分析瘤类型,包括质瘤,质母细胞瘤和脑膜瘤,并按年龄,性别和种族/种族分层数据.
主要成果:
- 所有初级恶性和非恶性脑和中枢神经系统瘤的年平均年龄调整发病率 (AAAIR) 在2018-2022年期间为每10万人口中的26.05.
- 发病率因性别和种族/种族而异,女性和非西班牙裔黑人个体的发病率更高.
- 质母细胞瘤是最常见的恶性瘤,而脑膜瘤是最常见的非恶性瘤. 总体死亡率为每10万人4.41,恶性瘤的5年生存率为34.8%,非恶性瘤的91.7%.
结论:
- 大脑和中枢神经系统瘤在美国是一个重大的公共卫生问题,具有明显的流行病学模式.
- 质母细胞瘤和脑膜瘤仍然是主要的组织病理学,突出了针对性研究和干预的领域.
- 存活率强调了对恶性脑和中枢神经系统瘤治疗的进步的急需.
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