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相关概念视频

Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

12.3K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Olfaction01:25

Olfaction

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
48.1K
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

11.2K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Osmoregulation in Insects01:47

Osmoregulation in Insects

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Malpighian tubules are specialized structures found in the digestive systems of many arthropods, including most insects, that handle excretion and osmoregulation. The tubules are typically arranged in pairs and have a convoluted structure that increases their surface area.
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Pollination and Flower Structure02:40

Pollination and Flower Structure

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Flowers are the reproductive, seed-producing structures of angiosperms. Typically, flowers consist of sepals, petals, stamens, and carpels. Sepals and petals are the vegetative flower organs. Stamens and carpels are the reproductive organs.  
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Tactile and Chemical Senses01:27

Tactile and Chemical Senses

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Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
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Single Sensillum Recordings for Locust Palp Sensilla Basiconica
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Single Sensillum Recordings for Locust Palp Sensilla Basiconica

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昆虫中的气味接收:功能和进化视角

Walter S Leal

    Annual review of entomology
    |October 15, 2025
    PubMed
    概括

    昆虫的气味是沟通的关键,推动了对昆虫如何使用专门的气味受体 (OR) 检测生存化合物的研究. 研究揭示了OR在嗅觉受体神经元 (ORNs) 中的演变和功能.

    科学领域:

    • 昆虫学 昆虫学是一门学科.
    • 化学生态化学生态学
    • 神经生物学 神经生物学 神经生物学
    • 结构生物学 结构生物学
    • 进化生物学 进化生物学

    背景情况:

    • 昆虫的沟通严重依赖于嗅觉线索,以获取与生存相关的化合物.
    • 香味受体 (ORs) 和费洛蒙结合蛋白已被结构性地表征,显示出特定的半化学相互作用.
    • 假设ORs是在陆地适应过程中从味觉受体进化出来的,并且专门用于激素检测.

    研究的目的:

    • 研究昆虫嗅觉和半化学检测背后的分子机制.
    • 探索昆虫嗅觉受体的进化和专业化.
    • 通过反向化学生态学识别新型半化学物质及其相应的受体.

    主要方法:

    • 结构生物学技术来解决蛋白质结构.
    • 基因沉默,异质系统中的表达,以及基因复活以研究受体功能.
    • 反向化学生态学方法用于半化学和受体发现.
    • 在嗅觉受体神经元 (ORN) 中对受体表达的分析.

    主要成果:

    • 对激素结合蛋白和气味受体 (ORs) 的结构洞察,使特定的连接体结合成为可能.

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    A Wind Tunnel for Odor Mediated Insect Behavioural Assays

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    Identification of Olfactory Volatiles using Gas Chromatography-Multi-unit Recordings GCMR in the Insect Antennal Lobe
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  • 支持ORs从味觉受体的进化轨迹的证据.
  • 检测受体de-orphanization和识别新的半化学物质.
  • 在ORN中确认ORs,核心受体和潜在的其他受体类型 (离子otropic, gustatory).
  • 结论:

    • 昆虫的嗅觉是一个复杂的系统,涉及多种不同的受体和蛋白质.
    • 气味受体已经显著进化,以调解关键的生存行为.
    • 像反向化学生态学这样的先进技术是理解昆虫与环境相互作用的强大工具.