在地震相关的创伤后应激障碍中增加碎片化QRS和降低基细胞
Dilek Örüm1, Yaşar Kapıcı2, Sabri Abuş2
1Elazığ Fethi Sekin City Hospital, Elazığ, Türkiye.
Journal of electrocardiology
|October 15, 2025
概括
电心电图 (ECG) 和全血细胞计 (CBC) 参数,包括碎片化QRS (fQRS) 和基细胞与淋巴细胞比率 (BLR),在2023年土耳其地震后患有创伤后应激障碍 (PTSD) 的人群中显著不同.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 血液学 血液学 血液学
背景情况:
- 2023年土耳其地震造成了广泛的创伤和精神疾病,特别是创伤后应激障碍 (PTSD).
- 了解地震幸存者的PTSD生理相关性对于诊断和管理至关重要.
研究的目的:
- 为了比较电心电图 (ECG) 参数,特别是碎片化QRS (fQRS) 和完整血清 (CBC) 参数,包括基础细胞与淋巴细胞比率 (BLR),在地震幸存者与没有PTSD之间进行比较.
- 为了确定地震相关PTSD的潜在生物标志物.
主要方法:
- 从47名地震幸存者中收集了心电图和心电图数据,其中47人患有PTSD,51人没有PTSD.
- 排除标准包括其他影响心电图/心血图的精神病和一般疾病.
- 经过验证的尺度 (PCL-5,SCL-90-R) 评估了PTSD的严重程度.
主要成果:
- 与没有PTSD的人相比,患有PTSD的个体表现出更高的SCL-90-R得分,fQRS数量和正面QRS-T角度.
- fQRS计数与PTSD严重程度 (PCL-5分数) 有显著的相关性.
- 基细胞计数显示了高的诊断准确性 (AUC 0.857),并且BLR是后勤回归的一个显著预测因素.
结论:
- 在地震幸存者与没有PTSD之间存在ECG (fQRS,前部QRS-T角度) 和CBC (基细胞计数,BLR) 参数的显著差异.
- 这些参数可以作为地震相关PTSD的潜在客观标志物.
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