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使用pH敏感探针ApHID实时绘制巨细胞溶解体的pH图像

Santiago Solé-Domènech1, Pradeep Kumar Singh1, Lucy Funes1

  • 1Department of Biochemistry and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.

Cell reports methods
|October 15, 2025
PubMed
概括

一个新的pH传感器,ApHID,准确地测量了内分泌体酸度. 这种探测器提供了更好的灵敏度和稳定性,克服了当前用于细胞成像的商业选择的局限性.

关键词:
这是一种虫虫 (aphid).CP: 细胞生物学 细胞生物学CP: 图像处理 图像处理这就是Dextrans.末解体体的pH值光探测器进行光探测.的pH值传感器.进行比度成像成像.

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相关概念视频

pH01:24

pH

The potential of hydrogen (pH) is a measure of the acidity or basicity of a water-based solution determined by the concentration of hydronium ions (H3O+). In one liter of pure water at neutral pH, there are 1×10−7 moles of hydronium ions. However, the extensive range of hydronium ion concentrations present in water-based solutions makes measuring pH in moles cumbersome. Therefore, a pH scale was developed to convert moles of hydronium ions into the negative logarithm of the hydronium ion...