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烟草吸烟:刺激血液体积的扩张
Alexandros Sotiridis1, Charalambos Dardamanis-Aidonas2, Anastasios Makris2
1Section of Sports Medicine and Biology of Exercise, School of Physical Education and Sport Science, National and Kapodistrian University of Athens, Athens, Greece; Hellenic Sports Research Institute, Athens Olympic Sports Center "Spyros Louis", Athens, Greece.
慢性吸烟者表现出血红蛋白质量和血液体积的增加,这可能是对一氧化碳 (CO) 暴露的生理适应. 然而,这种适应并不能改善,甚至可能损害受过训练的个体的耐力表现.
科学领域:
- 运动生理学 运动生理学
- 血液学 血液学 血液学
- 环境健康 环境健康
背景情况:
- 吸烟引入一氧化碳 (CO),形成碳氧血球蛋白 (COHb),并降低动脉氧含量.
- 目前尚不清楚吸烟者,即使是训练有素的个体,是否表现出血红蛋白质量 (HbM) 和血液体积的补偿性增加.
研究的目的:
- 为了调查慢性吸烟是否导致不同有氧健身水平的年轻男性的血红蛋白质量和血管内体积增加.
主要方法:
- 30名年轻男性被分为慢性吸烟者 (CS) 和非吸烟者 (NS),并根据有氧健身 (更适合[MF]和不适合[LF]).
- 使用一氧化碳 (CO) 重呼吸技术评估了血红蛋白质量 (HbM) 和血管内血量.
- 通过增量运行测试测量VO2峰值和峰值有氧速度;双向ANOVA分析差异.
主要成果:
- 与非吸烟者 (NS) 相比,吸烟者 (CS) 的HbM,总血液体积和红细胞体积显著增加.
- 在MF组中,有氧健身 (VO2峰值) 较高,在CS和LF组中,有氧峰值速度较低.
- 尽管吸烟者的HbM和血量增加,但耐力表现指标受损.
结论:
- 年轻男性的慢性吸烟,无论身体状况如何,都与增加的血红蛋白质量和血液体积有关.
- 吸烟者的这些血液学适应不增强,并且可能会对耐力表现产生负面影响.
- 需要进一步的研究来探索吸烟者的血红素调节.
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