冷大气等离子体用于气体治疗和气体激活药物输送
Qiaoyun Li1, Jaehyun Choi1, Namjo Shin1
1College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Advanced drug delivery reviews
|October 15, 2025
概括
冷大气等离子体 (CAP) 通过产生各种条件的反应性物种,提供有针对性的治疗效果. 需要进一步的研究来优化CAP的交付,并确保临床安全性和有效性.
科学领域:
- 生物医学工程 生物医学工程
- 等离子体物理学的物理学
- 医学科学 医学科学 医学科学
背景情况:
- 冷大气等离子体 (CAP) 是物质的第四种状态,它具有在位气体输送的独特特性.
- CAP产生反应性氧和物种 (RONS),对于氧化压力介导的治疗效果至关重要.
研究的目的:
- 审查当前的冷大气等离子体 (CAP) 输送方法及其生物医学应用.
- 探索CAP在各种疾病中的多样化治疗潜力.
- 讨论CAP与药物输送系统的整合以及未来的研究方向.
主要方法:
- 对CAP生成,属性和交付技术的当前文献的审查.
- 对CAP在不同医学领域的治疗效果的分析.
- 检查将CAP与先进的药物输送系统相结合的协同战略.
主要成果:
- 通过RONS生成,CAP在癌症治疗中表现出免疫调节效应,并在伤口愈合中表现出抗菌特性.
- 在口腔,炎症,胃肠道和神经疾病中,CAP通过消除生物膜,促进再生和调节氧化还原通路,显示出有效性.
- 通过将CAP与药物输送系统进行协同整合,可以提高治疗效果.
结论:
- 冷大气等离子体 (CAP) 在广泛的生物医学应用中具有显著的治疗潜力.
- 剂量控制,安全性和临床转化方面的挑战需要进一步调查.
- 未来的研究应该专注于优化CAP疗法,有针对性的治疗和临床验证以实现主流医疗整合.
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