大型语言模型作为适当抗微生物使用的信息提供者:计算文本分析和专家评级的ChatGPT,Claude和Gemini的比较
Marcello Di Pumpo1,2, Maria Rosaria Gualano3, Danilo Buonsenso4,5
1Section of Hygiene, University Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Campus di Roma, Rome, Lazio, Italy marcello.dipumpo@unicatt.it.
BMJ health & care informatics
|October 15, 2025
概括
大型语言模型 (LLM) 对健康信息有希望,双子座在内容质量和可访问性方面表现优于其他人. 然而,LLM需要专家监督医疗应用,特别是关于抗菌素耐药性的.
科学领域:
- 医疗保健中的人工智能
- 医疗信息学 医疗信息学
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球重大健康挑战.
- 大型语言模型 (LLM) 显示了传播健康信息的潜力.
- 评估LLM在抗生素使用和感染管理方面的有效性至关重要.
研究的目的:
- 评估领先的LLM在提供有关抗生素使用和感染管理的准确信息方面的表现.
- 为了比较不同LLM的内容质量,可读性和可访问性.
主要方法:
- 采用混合方法方法,分析LLM对专家设计的临床场景的反应.
- 计算式文本分析评估了可读性,词汇多样性和情感.
- 医学专家使用DISCERN工具评估了内容质量.
主要成果:
- 双子座在大多数指标上表现出卓越的表现,提供详细,可访问和多样化的内容,具有积极的基调.
- 聊天GPT 4.0表现出最高的词汇多样性.
- 所有模型都在努力提供有关抗菌素耐药性的充分信息,得分中位数为1.
结论:
- 虽然LLM显示出作为医疗信息的支持工具的潜力,但并不能取代医疗保健专业人员.
- 双子座展示了增强的内容质量和上下文意识.
- 专家监督和进一步的人工智能开发对于医疗保健中的安全和有效使用至关重要,特别是在AMR等关键领域.
相关概念视频
Antibiotic Selection
59.4K
Overview
59.4K
Leaky Scanning
5.6K
During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA. Marilyn Kozak discovered that the sequence RCCAUGG (where R...
5.6K
Antimicrobial Proteins
13.0K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
13.0K


