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Updated: Jan 15, 2026

Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
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老龄化改变了小鼠内源突变热点的基因组不稳定性

Alexandra M D'Amico1, Tonia T Li1, Dennis Wylie2

  • 1Division of Pharmacology and Toxicology, College of Pharmacy, Dell Pediatric Research Institute, The University of Texas at Austin, 1400 Barbara Jordan Boulevard, Austin, TX, 78723, USA.

Scientific reports
|October 15, 2025
PubMed
概括

老龄化增加了基因不稳定性,这是癌症风险因素. 这项研究表明,与年龄相关的DNA结构变化会在不同组织中不同影响突变率,影响癌症的发展.

关键词:
衰老的衰老 衰老的衰老癌症 癌症 癌症 癌症修复DNA的修复DNA的修复遗传不稳定性 遗传不稳定性这里是三重楼.

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