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Updated: Jan 15, 2026

One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode
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奥洛菲姆 (Olorofim) 是一种潜在的新型药物候选药物,用于对抗Helicobacter pylori感染

Saba Ghaffari1, Maryam Esmaeili1, Marjan Mohammadi2

  • 1HPGC Research Group, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.

The Journal of antibiotics
|October 15, 2025
PubMed
概括

奥洛菲姆有效地杀死Helicobacter pylori,包括抗生素耐药菌株,没有一般毒性. 然而,它并不准H. pylori DHODH酶,这表明这种有前途的候选药物的作用机制不同.

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