1990年至2021年的登革热全球负担:2021年全球疾病负担研究的系统分析
Jinxin Zheng1,2, Hai Tong1,2, Muxin Chen3
1School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Infectious diseases of poverty
|October 15, 2025
概括
全球范围内登革热负担正在增加,人口和地理差异很大. 有针对性的预防和控制策略对于应对这种日益严重的公共卫生挑战至关重要.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 公共卫生 公共卫生
背景情况:
- 登革热是一个重大的全球公共卫生挑战,发病率和负担不断增加.
- 全球变暖,城市化和旅行等因素加快了登革热的传播.
- 由于最近的数据有限,需要更新全球负担估计.
研究的目的:
- 量化全球趋势的变化和登革热的负担.
- 从1990-2021年分析登革热的发病率,流行率,死亡率和DALYs.
- 为了确定登革热影响的人口和地理差异.
主要方法:
- 利用2021年全球疾病负担 (GBD) 数据集进行分析.
- 从1990年到2021年,评估了204个国家/地区的登革热指标.
- 按年龄,性别和社会人口指数 (SDI) 分类的分层数据;采用年龄标准化率和回归分析.
主要成果:
- 从1990年到2021年,全球登革热负担增加了;年龄标准化发病率 (ASIR) 增加了0.56%.
- 在2021年,全球估计有58.96万名登革热病例发生.
- 热带拉丁美洲的ASIR最高;0-14岁的男性的DALY高;SDI的趋势有所不同,SDI低的地区下降.
结论:
- 登革热的负担在全球范围内不断增加,以人口和地理差异为标志.
- 调查结果强调,迫切需要量身定制的预防和控制战略.
- 有效的干预措施对于减轻日益升级的全球登革热负担至关重要.
相关概念视频
Principles of Disease Surveillance
460
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
460
Prevalence and Incidence
1.5K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.5K
Bias in Epidemiological Studies
1.3K
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
1.3K
Single Nucleotide Polymorphisms-SNPs
17.9K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
17.9K


