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Updated: Jan 15, 2026

Listeria monocytogenes Infection of the Brain

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Published on: October 2, 2018

散布的李斯特菌单细胞原体和人类佩吉病毒-1共感染

Man Yuan¹, Xiaoju Lv¹, Yu Yuan²

¹Center of Infectious Diseases, West China Hospital of Sichuan University, No. 37 Guoxue Alley Wuhou District, Chengdu, 610041, China.

BMC infectious diseases

|October 16, 2025

概括

本案例研究报告了在多发性骨髓瘤患者中首次与Listeria monocytogenes和人类佩吉病毒-1 (HPgV-1) 共同感染的情况. 这些发现突显了HPgV-1和脑膜炎之间的潜在联系,需要进一步调查.

科学领域:

传染性疾病传染性疾病
神经学神经学
病毒学病毒学

背景情况:

李斯特菌是细菌性脑膜炎的主要原因之一.
人类佩吉病毒-1 (HPgV-1) 的神经病理作用仍在争论中.
L. monocytogenes 和HPgV-1 之间的相互作用尚未得到充分了解.

研究的目的:

描述一种与L. monocytogenes和HPgV-1.一起感染的独特病例.
调查这种共感染的临床表现和诊断.

主要方法:

大脑脊髓液 (CSF) 的元基因组下一代测序 (mNGS).
在CSF和血液中检测L. monocytogenes和HPgV-1.
对L. monocytogenes的血液培养和对HPgV-1的PCR.

主要成果:

诊断HPgV-1和L. monocytogenes脑膜炎,HPgV-1病毒病和L. monocytogenes败血症的情况.
用美罗胺成功治疗.
患者的康复和医院出院.

结论:

这是第一次报告传播L. monocytogenes和HPgV-1共感染的病例.
需要进一步的研究,包括组织病理学分析,以确定HPgV-1在脑膜炎中的作用.

关键词:

人类佩吉病毒-1 李斯特里亚单细胞原生菌 (Listeria monocytogenes) 是一种脑膜炎是一种脑膜炎.败血症这是一种败血症.病毒性血病是什么意思

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