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tartaric 酸颗粒作为延长释放的核心:通过固体分散和因数设计的开发

Amanda Moscibroski da Silva Bedin1,2, Jéssika Adriane Janning2, Volnei José Tondo2

  • 1Postgraduate Program in Pharmaceutical Sciences of the State University of Western Paraná, Cascavel, Paraná, Brazil.

Drug development and industrial pharmacy
|October 16, 2025
PubMed
概括

这项研究开发了一种延长释放的西尔代纳菲尔酸盐 (SC) 配方,以改善肺动脉高血压 (PAH) 治疗的溶解性和生物可用性. 这种新型系统显著提高了SC溶解度,并提供持续释放,可能改善患者的治疗结果.

关键词:
肺动脉高血压是肺动脉高血压.延长释放放出的延长释放口服生物可用性 口服生物可用性固体分散的散发方式tartaric 酸 颗粒 葡萄酒酸 颗粒

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