老年人认知障碍的基于步态的查:一种快速而客观的方法
Jose Luis Perez-Lasierra1,2, Marina Azpíroz-Puente1, Martin Morita-Hernandez1
1Podoactiva Biomechanical Unit, Research & Development Department, Parque Tecnológico Walqa, Ctra. N330a Km 566, 22197 Cuarte, Spain.
Healthcare (Basel, Switzerland)
|October 16, 2025
概括
步态分析有效地选老年人的认知障碍. 使用步长和双支持时间的算法显示出高准确度,提供了快速,客观的临床工具.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 生物机械工程 生物机械工程
背景情况:
- 认知障碍在老年人群中越来越令人担忧.
- 目前的查方法耗时,需要临床专业知识.
- 步态分析为早期检测提供了一个有希望的,客观的替代方案.
研究的目的:
- 确定与老年人认知障碍相关的步态变量.
- 开发预测算法,以区分残疾人和非残疾人.
- 验证步态分析作为黄金标准选工具.
主要方法:
- 对42名60岁以上的成年人进行横截面研究.
- 通过迷你精神状态检查 (MMSE) 评估认知功能.
- 使用Optogait系统测量时空步行参数;开发和验证后勤回归模型.
主要成果:
- 使用步长和双支持时间的算法显示了高分类性能.
- 培训组的AUC-ROC为0.91 (灵敏度为71.4%,特异性为92.3%).
- 验证组显示AUC-ROC为0.84,准确度为81.0%.
结论:
- 黄金标准步态分析有效地识别了老年人的认知障碍.
- 开发的算法提供了一个快速,客观和准确的选替代方案.
- 在早期认知衰退检测中具有重大临床应用的潜力.
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