高血压管理中的光生物调节疗法 - - 来自系统审查和元分析的证据
Lara Maria Bataglia Espósito1, Francisco Costa da Rocha1, Praveen R Arany2
1Physical Therapy Department, Federal University of São Carlos (UFSCar), São Carlos, 13565-905, SP, Brazil.
Journal of clinical medicine
|October 16, 2025
概括
光生物调制 (PBM) 疗法可以通过潜在降低血压 (BP) 和心率 (HR) 来帮助控制高血压. 然而,由于研究中的偏见很高,目前的证据的确定性非常低.
科学领域:
- 心血管研究研究心血管研究
- 生物医学工程 生物医学工程
- 照相医疗 (photomedicine) 是一种医学技术.
背景情况:
- 高血压对健康构成重大风险,导致高死亡率.
- 对许多高血压患者来说,控制血压 (BP) 仍然是一个挑战.
- 光生物调制 (PBM) 疗法正在成为高血压管理的潜在干预措施.
研究的目的:
- 系统地审查和分析关于PBM治疗在治疗高血压方面的有效性现有证据.
- 评估PBM在降低血压和其他心血管参数方面的实用性.
主要方法:
- 随机临床试验 (RCT) 和实验动物研究的系统审查和元分析.
- 搜索了五个主要数据库,对数据进行了描述性和定量分析.
- 包括四个RCT和五个实验研究,在选了197篇文章后.
主要成果:
- 临床试验表明,PBM降低了缩血压 (SBP),腹缩血压 (DBP) 和心率 (HR) 的确定性非常低.
- 实验研究表明,PBM降低了SBP,DBP和平均动脉压 (MAP),增加了氧化水平,也很低的确定性.
- 试验试验显示有偏差的高风险,而实验研究的偏差风险不清楚.
结论:
- PBM治疗显示出作为高血压的辅助治疗的潜力,可能减少SBP,DBP,MAP和HR.
- 目前支持PBM治疗高血压的证据的确定性非常低.
- 需要进一步严格,精心设计的临床和实验研究来提高证据质量.
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