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化耳朵在上腺功能缺陷:系统文献综述
Elisa Jörg1, Gregorio P Milani2,3, Sebastiano A G Lava4
1Family Medicine Institute, Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6900 Lugano, Switzerland.
Journal of clinical medicine
|October 16, 2025
概括
石化耳朵是一种影响成年男性的双边疾病,与上腺功能不全有关. 它发生在初级和中央形式,并没有改善治疗,经常出现在诊断后的几年初级病例.
科学领域:
- 内分泌学 在内分泌学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 皮肤病学 皮肤病学
背景情况:
- 上腺功能不全是一种与石化耳朵相关的已知的疾病.
- 为了进一步探索这种关联,进行了系统的文献审查.
研究的目的:
- 为了研究上腺功能不全患者石化耳朵的特征和临床表现.
- 为了区分初级与中央上腺功能不全中石化耳朵的发生情况.
主要方法:
- 按照PRISMA指南进行系统的文献审查.
- 搜索了Excerpta Medica,PubMed和Web of Science数据库,没有语言限制.
- 包括报告上腺功能衰竭和石化耳朵的研究,提取人口统计,临床和结果数据.
主要成果:
- 分析了36份报告中的40例病例,主要影响成年男性 (38/40).
- 石化耳朵在所有病例中都是双边的,并且发生在初级 (18例) 和中央 (20例) 上腺功能不全中.
- 在原发性上腺功能衰竭中,石化耳朵在诊断后≥2年出现 (72%);在中心功能衰竭中,它与诊断同时或之前 (85%).
结论:
- 上腺功能衰竭中的石化耳朵始终是双边的,影响成年男性,并且在初级和中央形式中观察到.
- 石化耳朵检测的时间在初级 (后期) 和中央 (早期/同时) 上腺功能不全之间有所不同.
- 与上腺功能不充分相关的石化耳朵不会通过治疗得到改善,也不与听力损伤有关.
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